Protein Modification Reagents
![Medchemexpress LLC Propanoic acid, 3-[[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]- | 1309460-27-2 | MFCD18916985 | 99.1% | 397.42 g/mol | C19H27NO8 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202266.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]- | 1309460-27-2 | MFCD18916985 | 99.1% | 397.42 g/mol | C19H27NO8 | 1 G
A noncleavable polyethylene glycol (PEG) linker intended for antibody-drug conjugate research. It provides a 4-unit PEG spacer with an aldehyde-phenyl amido linkage and a terminal carboxylic acid for bioconjugation; supplied as a viscous, off-white to light yellow liquid with high purity and specific storage requirements.
- Noncleavable linker for antibody-drug conjugate research.
- High purity: 99.1%.
- Molecular weight: 397.42 g/mol.
- Chemical formula: C19H27NO8.
- CAS number: 1309460-27-2.
- Appearance: viscous liquid, off-white to light yellow.
- Storage: store at 4°C under nitrogen; in solution, -20°C (short term) or -80°C (long term).
- Packaged quantity: 1 G.
Worthington Biochemical Corporation Collagenase, Type 3, 5g
Lower in secondary proteolytic contaminant activities but with typical collagenase activity. Suggested for mammary primary cell isolation. A dialyzed, lyophilized powder. Store at 2-8°C.
Medchemexpress LLC Endo-BCN-PEG2-alcohol | 1807501-85-4 | 98.0% | 325.40 | 100 MG
endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs consist of two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein. PROTACs degrade target proteins using the intracellular ubiquitin-proteasome system.
- Purity: 98.0%
- Molecular weight: 325.40
- Formula: C17H27NO5
- Appearance: Oil
- Color: Colorless to light yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: -20°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)
Medchemexpress LLC Biotin-PEG2-alkyne | 2227450-68-0 | MFCD31922733 | 95.6% | 369.48 g/mol | C17H27N3O4S | 100 MG
Biotin-PEG2-alkyne is a short polyethylene glycol (PEG) linker functionalized with a biotin group and a terminal alkyne. It is designed for affinity-based capture and copper(I)-catalyzed azide-alkyne cycloaddition (click chemistry) conjugations in research applications.
- Contains a biotin moiety for affinity capture.
- Includes a terminal alkyne for copper(I)-catalyzed click chemistry.
- Short PEG2 linker improves solubility and reduces steric hindrance.
- Supplied as an off-white to light yellow solid.
- Purity 95.6% by supplier specification.
- Suitable for pull-down assays and biotinylation workflows.
- Store powder at -20°C for long-term stability; 4°C for shorter storage.
Medchemexpress LLC Bis-PEG4-PFP ester | 1314378-12-5 | 97.0% | 10 G
Bis-PEG4-PFP ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker, one for an E3 ubiquitin ligase and another for a target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Exploits the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
Echelon Biosciences Research Labs Pancreatic Elastase Substrate, human - 5 mg,
Pancreatic Elastase Substrate, human - 5mg , Succinyl-Ala-Ala-Pro-Phe-AFC Category/Application: Enzyme Substrates This item is non returnable
Medchemexpress LLC Amino-PEG4-GGFG-Dxd | 2879227-88-8 | MFCD09950912 | 100.0% | 1088.14 | C53H66FN9O15 | 1 MG
Amino-PEG4-GGFG-Dxd is a drug-linker conjugate designed for the synthesis of antibody-drug conjugates (ADCs). It consists of the DXd cytotoxic payload connected via a PEG4-GGFG peptide linker with a terminal amino group, and is supplied as an off-white to light yellow solid for research use only.
- Drug-linker conjugate intended for ADC synthesis.
- Contains DXd (an exatecan derivative) as the cytotoxic payload.
- PEG4-GGFG peptide linker provides spacer and protease-cleavable sequence.
- Terminal amino group enables conjugation to activated linkers or antibodies.
- High stated purity and solid form suitable for research applications.